PDE4B anticorps (AA 189-217)

N° du produit ABIN655630

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE4B dans WB et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour PDE4B anticorps (AA 189-217) (ABIN655630)

Antigène: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE4B est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB18545

Détail du produit anti-PDE4B anticorps

Épitope: AA 189-217

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur PDE4B

Antigène: PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))

Autre désignation: PDE4B

Sujet: This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Poids moléculaire: 83343

ID gène: 5142

NCBI Accession: NP_001032416, NP_001032417, NP_001032418, NP_002591

UniProt: Q07343

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction