HAX1 anticorps (C-Term)

N° du produit ABIN656245

Cet anticorps Lapin Polyclonal détecte spécifiquement HAX1 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour HAX1 anticorps (C-Term) (ABIN656245)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31099

Détail du produit anti-HAX1 anticorps

Épitope: AA 161-190, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the C-terminal region of human HAX1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: HAX1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1

Sujet: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 31621

ID gène: 10456

NCBI Accession: NP_001018238, NP_006109

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization