Surfactant Protein C anticorps (N-Term)
Aperçu rapide pour Surfactant Protein C anticorps (N-Term) (ABIN656267)
Antigène
Voir toutes Surfactant Protein C (SFTPC) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-30, N-Term
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Homologie
- B
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.
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Isotype
- IgG
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Indications d'application
- IF: 1:25. WB: 1:2000. FC: 1:25
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- SFTPC Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- Surfactant Protein C (SFTPC)
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Autre désignation
- SFTPC
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Sujet
- This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90 % lipids and 10 % proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.
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Poids moléculaire
- 21053
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ID gène
- 6440
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NCBI Accession
- NP_001165828, NP_001165881, NP_003009
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UniProt
- P11686
Antigène
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