SESN3 anticorps (AA 320-347)

N° du produit ABIN656403

Cet anticorps anti-SESN3 est un anticorps Lapin Polyclonal détectant SESN3 dans WB et IHC (p). Adapté pour Humain. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour SESN3 anticorps (AA 320-347) (ABIN656403)

Antigène: SESN3 (Sestrin 3 (SESN3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SESN3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB18605

Détail du produit anti-SESN3 anticorps

Épitope: AA 320-347

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Sestrin-3 Antibody (Center Y335) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-SESN3 (ABIN656403)

Kimball, Ravi, Gordon, Dennis, Jefferson: "Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet." dans: The Journal of nutrition, Vol. 145, Issue 11, pp. 2496-502, (2015) (PubMed).

Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." dans: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).

Détails sur SESN3

Antigène: SESN3 (Sestrin 3 (SESN3))

Autre désignation: Sestrin-3

Sujet: Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.

Poids moléculaire: 57291

ID gène: 143686

NCBI Accession: NP_653266

UniProt: P58005