SESN3 anticorps (AA 320-347)

N° du produit ABIN656403

Détail du produit anti-SESN3 anticorps

Antigène: SESN3 (Sestrin 3 (SESN3))

Épitope: AA 320-347

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SESN3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3.

Clone: RB18605

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Sestrin-3 Antibody (Center Y335) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-SESN3 (ABIN656403)

Kimball, Ravi, Gordon, Dennis, Jefferson: "Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet." dans: The Journal of nutrition, Vol. 145, Issue 11, pp. 2496-502, (2015) (PubMed).

Ye, Palm, Peng, King, Lindsten, Li, Koumenis, Thompson: "GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2." dans: Genes & development, Vol. 29, Issue 22, pp. 2331-6, (2015) (PubMed).

Détails sur SESN3

Antigène: SESN3 (Sestrin 3 (SESN3))

Autre désignation: Sestrin-3 (SESN3 Produits)

Synonymes: anticorps cb261, anticorps sb:cb261, anticorps zgc:56722, anticorps wu:fb77c04, anticorps wu:fc41d03, anticorps wu:fd59d12, anticorps sestrin-3, anticorps sest3, anticorps SEST3, anticorps 5630400E15Rik, anticorps BC003348, anticorps sestrin 3, anticorps sestrin 3 L homeolog, anticorps SESN3, anticorps sesn3, anticorps sesn3.L, anticorps Sesn3

Sujet: Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.

Poids moléculaire: 57291

ID gène: 143686

NCBI Accession: NP_653266

UniProt: P58005