FAP anticorps

N° du produit ABIN656472

Cité dans 1 publication. Cet anticorps anti-FAP Polyclonal Lapin (Clone RB07288) (ABIN656472) détecte spécifiquement FAP dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FAP anticorps (ABIN656472)

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAP est non-conjugé

Application: Western Blotting (WB)

Clone: RB07288

Détail du produit anti-FAP anticorps

Purification: This antibody is purified through a protein A column, followed by dialysis against PBS.

Immunogène: This FAP antibody is generated from rabbits immunized with the protein of human FAP.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: His6-FAP Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-FAP (ABIN656472)

Yang, Lin, Shi, Li, Liu, Yin, Dang, Chu, Fan, He: "FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling." dans: Cancer research, Vol. 76, Issue 14, pp. 4124-35, (2016) (PubMed).

Détails sur FAP

Antigène: FAP (Fibroblast Activation Protein, alpha (FAP))

Autre désignation: FAP

Sujet: The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Poids moléculaire: 87713

ID gène: 2191

NCBI Accession: NP_004451

UniProt: Q12884

Pathways: Tube Formation