Melanophilin anticorps (C-Term)

N° du produit ABIN656542

Détail du produit anti-Melanophilin anticorps

Antigène: Melanophilin (MLPH)

Épitope: AA 541-569, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Melanophilin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MLPH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 541-569 amino acids from the C-terminal region of human MLPH.

Clone: RB32075

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: MLPH Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur Melanophilin

Antigène: Melanophilin (MLPH)

Autre désignation: MLPH (MLPH Produits)

Synonymes: anticorps MGC155106, anticorps LOC100222096, anticorps 2210418F23Rik, anticorps 5031433I09Rik, anticorps AW228792, anticorps D1Wsu84e, anticorps Slac-2a, anticorps l(1)-3Rk, anticorps l1Rk3, anticorps ln, anticorps SLAC2-A, anticorps melanophilin, anticorps MLPH, anticorps mlph, anticorps Mlph

Sujet: This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Poids moléculaire: 65949

ID gène: 79083

NCBI Accession: NP_001035932, NP_001268402, NP_077006

UniProt: Q9BV36