TMEM43 anticorps (AA 195-223)
Aperçu rapide pour TMEM43 anticorps (AA 195-223) (ABIN2845811)
Antigène
Voir toutes TMEM43 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 195-223
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Homologie
- M, Rat
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. IHC-P: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- TMEM43 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- TMEM43 (Transmembrane Protein 43 (TMEM43))
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Autre désignation
- TMEM43
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Sujet
- This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
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Poids moléculaire
- 44876
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ID gène
- 79188
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NCBI Accession
- NP_077310
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UniProt
- Q9BTV4
Antigène
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