FAM33A anticorps (N-Term)

N° du produit ABIN656609

L’anticorps anti-FAM33A Polyclonal Lapin est utilisé pour la détection de FAM33A dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour FAM33A anticorps (N-Term) (ABIN656609)

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM33A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB31468

Détail du produit anti-FAM33A anticorps

Épitope: AA 9-37, N-Term

Homologie: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This SKA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-37 amino acids from the N-terminal region of human SKA2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: SKA2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur FAM33A

Antigène: FAM33A (Spindle and Kinetochore-Associated Protein 2 (FAM33A))

Autre désignation: SKA2

Sujet: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it is required for SKA1 localization.

Poids moléculaire: 14188

ID gène: 348235

NCBI Accession: NP_001094065, NP_872426

UniProt: Q8WVK7

Pathways: M Phase