ZP4 anticorps (C-Term)

N° du produit ABIN2845893

Cité dans 1 publication. Cet anticorps anti-ZP4 Polyclonal Lapin (Clone RB32332) (ABIN2845893) détecte spécifiquement ZP4 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ZP4 anticorps (C-Term) (ABIN2845893)

Antigène: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZP4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB32332

Détail du produit anti-ZP4 anticorps

Épitope: AA 445-474, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ZP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ZP4.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: ZP4 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Références pour anticorps anti-ZP4 (ABIN2845893)

Mask, Schoenecker, Kane, Ransom, Bruemmer: "Serum antibody immunoreactivity to equine zona protein after SpayVac vaccination." dans: Theriogenology, Vol. 84, Issue 2, pp. 261-7, (2015) (PubMed).

Détails sur ZP4

Antigène: ZP4 (Zona Pellucida Glycoprotein 4 (ZP4))

Autre désignation: ZP4

Sujet: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4.

Poids moléculaire: 59400

ID gène: 57829

NCBI Accession: NP_067009

UniProt: Q12836