IRF4 anticorps

N° du produit ABIN6566604

Cet anticorps Lapin Polyclonal détecte spécifiquement IRF4 dans WB. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour IRF4 anticorps (ABIN6566604)

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IRF4 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human IRF4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IRF4

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: IRF4

Sujet:

Synonyms: Interferon regulatory factor 4,IRF 4,IRF-4,Irf4,IRF4,LSIRF,Lymphocyte specific interferon regulatory factor,Lymphocyte specific IRF,Lymphocyte-specific interferon regulatory factor,Multiple myeloma oncogene 1,MUM 1,MUM1,NF EM5,NF-EM5,NFEM5,PU.1 interaction partner,Sfpi1/PU.1 interaction partner,Transcriptional activator PIP

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 52kDa

Calculated_MW: 51kDa

ID gène: 3662

UniProt: Q15306

Pathways: Chromatin Binding