CRLF2 anticorps

N° du produit ABIN6566796

Cet anticorps Lapin Polyclonal détecte spécifiquement CRLF2 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CRLF2 anticorps (ABIN6566796)

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRLF2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CRLF2 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human CRLF2

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CRLF2

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Autre désignation: CRLF2

Sujet:

Synonyms: CRL 2,CRL2,CRLF 2,Crlf2,CRLF2,CRLF2Y,Cytokine receptor CRL2 precusor,Cytokine receptor like 2,Cytokine receptor like factor 2,Cytokine receptor like factor 2 precursor,Cytokine receptor-like 2,Cytokine receptor-like factor 2,IL XR,IL-XR,ILXR,Thymic stromal derived lymphopoietin receptor,Thymic stromal lymphopoietin protein receptor,Thymic stromal lymphopoietin receptor,TSLP receptor,TSLPR

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire:

Observed_MW: 50kDa

Calculated_MW: 26kDa/29kDa/42kDa

ID gène: 64109

UniProt: Q9HC73