LMAN1 anticorps

N° du produit ABIN6566931

L’anticorps Lapin Polyclonal anti-LMAN1 a été validé pour WB. Il convient pour détecter LMAN1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour LMAN1 anticorps (ABIN6566931)

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LMAN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LMAN1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human LMAN1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LMAN1

Antigène: LMAN1 (Lectin, Mannose-Binding, 1 (LMAN1))

Autre désignation: LMAN1

Sujet:

Synonyms: Endoplasmic reticulum golgi intermediate compartment protein 53 ,ER-Golgi intermediate compartment 53 kDa protein,ERGIC-53,ERGIC53,ERGIC53 like protein,F5F8D,FMFD1,Gp58,Intracellular mannose specific lectin ,Intracellular mannose-specific lectin MR60,Lectin mannose binding 1 ,Lectin mannose-binding 1,Lman1,LMAN1 like protein ,LMAN1,MCFD1,MR60,Protein ERGIC-53

Background: The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and  pH -sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.

Poids moléculaire:

Observed_MW: 55kDa

Calculated_MW: 57kDa

ID gène: 3998

UniProt: P49257