Ataxin 3 anticorps

N° du produit ABIN6567724

Cet anticorps anti-Ataxin 3 est un anticorps Lapin Polyclonal détectant Ataxin 3 dans WB et IF. Adapté pour Humain et Souris.

Aperçu rapide pour Ataxin 3 anticorps (ABIN6567724)

Antigène: Ataxin 3 (ATXN3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Ataxin 3 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-Ataxin 3 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human ATXN3

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Ataxin 3

Antigène: Ataxin 3 (ATXN3)

Autre désignation: ATXN3

Sujet:

Synonyms: AT3,Ataxin 3,ataxin 3 variant h,ataxin 3 variant m,ataxin 3 variant ref,Ataxin-3,ATX3,ATX3,ATXN3,EC 3.4.22.,JOS,Josephin,Machado Joseph disease (spinocerebellar ataxia 3,olivopontocerebellar ataxia 3,autosomal dominant,ataxin 3),Machado Joseph disease,Machado Joseph disease protein 1,Machado-Joseph disease protein 1,Machado-Joseph disease protein 1 homolog,MJD,MJD gene,MJD1,Olivopontocerebellar ataxia 3,OTTHUMP00000221583,OTTHUMP00000221585,OTTHUMP00000221586,OTTHUMP00000221587,OTTHUMP00000231995,OTTHUMP00000231997,Rsca3,SCA3,SCA3 gene,Spinocerebellar ataxia type 3 protein

Background: Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire:

Observed_MW: 50kDa

Calculated_MW: 20kDa/35kDa/39kDa/41kDa

ID gène: 4287

UniProt: P54252