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ALAS1 anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement ALAS1 dans IF. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN6567981

Aperçu rapide pour ALAS1 anticorps (ABIN6567981)

Antigène

Voir toutes ALAS1 Anticorps
ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Reactivité

  • 54
  • 23
  • 23
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 53
  • 3
Lapin

Clonalité

  • 42
  • 14
Polyclonal

Conjugué

  • 25
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ALAS1 est non-conjugé

Application

  • 36
  • 13
  • 10
  • 9
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Immunofluorescence (IF)
  • Purification

    Affinity purification

    Immunogène

    Recombinant fusion protein of human ALAS1 (NP_954635.1).

    Isotype

    IgG
  • Indications d'application

    IF 1:50-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

    Autre désignation

    ALAS1

    Sujet

    This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Poids moléculaire

    Observed_MW: Refer to figures

    Calculated_MW: 12kDa/70kDa

    ID gène

    211

    UniProt

    P13196

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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