TRIM21 anticorps

N° du produit ABIN6568036

Cet anticorps Lapin Polyclonal détecte spécifiquement TRIM21 dans IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TRIM21 anticorps (ABIN6568036)

Antigène: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRIM21 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TRIM21 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human TRIM21

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50 - 1:200 IF 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TRIM21

Antigène: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Autre désignation: TRIM21

Sujet:

Synonyms: 52 kDa ribonucleoprotein autoantigen Ro/SS-A,52 kDa Ro protein,52kD Ro/SSA autoantigen,Autoantigen Ro/SSA,52-KD,E3 ubiquitin-protein ligase TRIM21,RING finger protein 81,RNF81,Ro 52,Ro(SS-A),Ro52,RO52,Sicca syndrome antigen A,Sjoegren syndrome type A antigen,Sjogren syndrome antigen A1,Sjogren syndrome type A antigen,SS-A,SSA,SSA1: Sjogren syndrome antigen A1 (52  kDa ribonucleoprotein autoantigen SS-A/Ro),TRIM21,Tripartite motif protein TRIM21,Tripartite motif-containing 21,Tripartite motif-containing protein 21

Background: This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 45kDa/54kDa

ID gène: 6737

UniProt: P19474