Dynamitin anticorps (AA 192-219)

N° du produit ABIN656819

L’anticorps Lapin Polyclonal anti-Dynamitin a été validé pour WB et IHC (p). Il convient pour détecter Dynamitin dans des échantillons de Humain.

Aperçu rapide pour Dynamitin anticorps (AA 192-219) (ABIN656819)

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamitin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB19599

Détail du produit anti-Dynamitin anticorps

Épitope: AA 192-219

Homologie: B, M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: DCTN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur Dynamitin

Antigène: Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

Autre désignation: DCTN2

Sujet: This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.

Poids moléculaire: 44231

ID gène: 10540

NCBI Accession: NP_001248341, NP_001248342, NP_006391

UniProt: Q13561

Pathways: M Phase, Ribonucleoprotein Complex Subunit Organization