PRAME anticorps

N° du produit ABIN6568373

L’anticorps Lapin Polyclonal anti-PRAME a été validé pour WB. Il convient pour détecter PRAME dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PRAME anticorps (ABIN6568373)

Antigène: PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRAME est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PRAME anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human PRAME

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PRAME

Antigène: PRAME (Preferentially Expressed Antigen in Melanoma (PRAME))

Autre désignation: PRAME

Sujet:

Synonyms: 4930534P07Rik,Cancer/testis antigen 130,CT130,MAPE,Melanoma antigen preferentially expressed in tumors,OIP 4,OIP-4,OIP4 ,OPA interacting protein 4,Opa interacting protein OIP4,OPA-interacting protein 4,PRAME,PRAME,Preferentially expressed antigen in melanoma ,Preferentially expressed antigen of melanoma,RP23-250F8.3

Background: This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 58kDa

Calculated_MW: 57kDa

ID gène: 23532

UniProt: P78395

Pathways: Retinoic Acid Receptor Signaling Pathway, Nuclear Hormone Receptor Binding