DAD1 anticorps
Aperçu rapide pour DAD1 anticorps (ABIN6568449)
Antigène
Voir toutes DAD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide of human DAD1
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- DAD1 (Defender Against Cell Death 1 (DAD1))
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Autre désignation
- DAD1
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Sujet
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Synonyms: DAD 1,DAD-1,dad1,DAD1,Defender against cell death 1,Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,Oligosaccharyl transferase subunit DAD1,OST 2,OST2
Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.
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Poids moléculaire
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Observed_MW: 22kDa
Calculated_MW: 12kDa
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ID gène
- 1603
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UniProt
- P61803
Antigène
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