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DAD1 anticorps

Cet anticorps anti-DAD1 est un anticorps Lapin Polyclonal détectant DAD1 dans WB. Adapté pour Humain, Souris et Rat.
N° du produit ABIN6568449

Aperçu rapide pour DAD1 anticorps (ABIN6568449)

Antigène

Voir toutes DAD1 Anticorps
DAD1 (Defender Against Cell Death 1 (DAD1))

Reactivité

Humain, Souris, Rat

Hôte

  • 42
  • 2
Lapin

Clonalité

  • 43
  • 1
Polyclonal

Conjugué

  • 12
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DAD1 est non-conjugé

Application

  • 21
  • 16
  • 13
  • 13
  • 8
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Purification

    Affinity purification

    Immunogène

    A synthetic peptide of human DAD1

    Isotype

    IgG
  • Indications d'application

    WB 1:500 - 1:2000

    Restrictions

    For Research Use only
  • Concentration

    1 mg/mL

    Buffer

    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène

    DAD1 (Defender Against Cell Death 1 (DAD1))

    Autre désignation

    DAD1

    Sujet

    Synonyms: DAD 1,DAD-1,dad1,DAD1,Defender against cell death 1,Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1,Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1,Oligosaccharyl transferase subunit DAD1,OST 2,OST2

    Background: DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes.

    Poids moléculaire

    Observed_MW: 22kDa

    Calculated_MW: 12kDa

    ID gène

    1603

    UniProt

    P61803
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