RASD1 anticorps
Aperçu rapide pour RASD1 anticorps (ABIN6568710)
Antigène
Voir toutes RASD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human RASD1
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Isotype
- IgG
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Indications d'application
- WB 1:200 - 1:2000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))
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Autre désignation
- RASD1
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Sujet
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Synonyms: Activator of G protein signaling 1,Activator of G protein signaling,Activator of G-protein signaling 1,AGS 1,AGS1,Dexamethasone induced ras related protein 1,Dexamethasone-induced ras protein 1,Dexamethasone-induced Ras-related protein 1,Dexras 1,MGC:26290,RAS dexamethasone induced 1,Ras protein, Dexamethasone-induced, 1,Ras related protein,RASD 1,Rasd1,RASD1
Background: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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Poids moléculaire
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Observed_MW: 31kDa
Calculated_MW: 13kDa/31kDa
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ID gène
- 51655
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UniProt
- Q9Y272
Antigène
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