NTAN1 anticorps

N° du produit ABIN6568757

L’anticorps Lapin Polyclonal anti-NTAN1 a été validé pour WB. Il convient pour détecter NTAN1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NTAN1 anticorps (ABIN6568757)

Antigène: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NTAN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-NTAN1 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human NTAN1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur NTAN1

Antigène: NTAN1 (N-terminal Asparagine Amidase (NTAN1))

Autre désignation: NTAN1

Sujet:

Synonyms: N terminal Asn amidase,N terminal asparagine amidase ,N terminal asparagine amidohydrolase,NTN-amidase,PNAA ,PNAD ,Protein N-terminal Asn amidase,Protein N-terminal asparagine amidase,Protein N-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase

Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Poids moléculaire:

Observed_MW: 35kDa

Calculated_MW: 34kDa

ID gène: 123803

UniProt: Q96AB6