NTAN1 anticorps
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- Antigène Voir toutes NTAN1 Anticorps
- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
- Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NTAN1 est non-conjugé
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogène
- Recombinant protein of human NTAN1
- Isotype
- IgG
- Top Product
- Discover our top product NTAN1 Anticorps primaire
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- Indications d'application
- WB 1:200 - 1:2000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- NTAN1 (N-terminal Asparagine Amidase (NTAN1))
- Autre désignation
- NTAN1 (NTAN1 Produits)
- Synonymes
- anticorps PNAA, anticorps PNAD, anticorps N-terminal Asn amidase, anticorps N-terminal asparagine amidase, anticorps Ntan1, anticorps NTAN1
- Sujet
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Synonyms: N terminal Asn amidase,N terminal asparagine amidase ,N terminal asparagine amidohydrolase,NTN-amidase,PNAA ,PNAD ,Protein N-terminal Asn amidase,Protein N-terminal asparagine amidase,Protein N-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine amidohydrolase,Protein NH2-terminal asparagine deamidase,Protein NTN-amidase
Background: The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
- Poids moléculaire
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Observed_MW: 35kDa
Calculated_MW: 34kDa
- ID gène
- 123803
- UniProt
- Q96AB6
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