TIMP2 anticorps
Aperçu rapide pour TIMP2 anticorps (ABIN5963767)
Antigène
Voir toutes TIMP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- A synthetic peptide of human TIMP2 (NP_003246.1).
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:2000 IF 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Autre désignation
- TIMP2
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Sujet
- This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
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Poids moléculaire
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Observed_MW: 22kDa
Calculated_MW: 24kDa
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ID gène
- 7077
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UniProt
- P16035
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Pathways
- cAMP Metabolic Process
Antigène
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