CHRNA4 anticorps

N° du produit ABIN6568827

Cet anticorps Lapin Polyclonal détecte spécifiquement CHRNA4 dans WB. Il présente une réactivité envers Souris.

Aperçu rapide pour CHRNA4 anticorps (ABIN6568827)

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHRNA4 anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human CHRNA4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CHRNA4

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Autre désignation: CHRNA4

Sujet: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 75kDa

Calculated_MW: 60kDa/69kDa

ID gène: 1137

UniProt: P43681

Pathways: Synaptic Membrane