CHRNA4 anticorps

N° du produit ABIN6568827

Détail du produit anti-CHRNA4 anticorps

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHRNA4 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein of human CHRNA4

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CHRNA4

Antigène: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Autre désignation: CHRNA4 (CHRNA4 Produits)

Synonymes: anticorps NACHRA4, anticorps BFNC, anticorps EBN, anticorps EBN1, anticorps NACHR, anticorps NACRA4, anticorps NARAC, anticorps Acra-4, anticorps Acra4, anticorps ENFL1, anticorps neuronal acetylcholine receptor subunit alpha-4, anticorps neuronal acetylcholine receptor subunit alpha-4-like, anticorps cholinergic receptor nicotinic alpha 4 subunit, anticorps cholinergic receptor, nicotinic, alpha 4b, anticorps cholinergic receptor, nicotinic, alpha polypeptide 4, anticorps CpipJ_CPIJ002434, anticorps LOC100368057, anticorps CHRNA4, anticorps chrna4b, anticorps Chrna4

Sujet: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Poids moléculaire:

Observed_MW: 75kDa

Calculated_MW: 60kDa/69kDa

ID gène: 1137

UniProt: P43681

Pathways: Synaptic Membrane