PHD1 anticorps

N° du produit ABIN6569199

L’anticorps Lapin Polyclonal anti-PHD1 a été validé pour WB et IP. Il convient pour détecter PHD1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PHD1 anticorps (ABIN6569199)

Antigène: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHD1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PHD1 anticorps

Purification: Affinity purification

Immunogène: A synthetic peptide of human EGLN2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000 IP 1:20 - 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PHD1

Antigène: PHD1 (EGLN2) (Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))

Autre désignation: EGLN2

Sujet:

Synonyms: DKFZp434E026,EGL nine (C.elegans) homolog 2,Egl nine homolog 2 (C. elegans),Egl nine homolog 2,EGLN 2,EGLN2,EGLN2,EIT 6,EIT6,Estrogen-induced tag 6,HIF P4H 1,HIF PH1,HIF prolyl hydroxylase 1,HIF-PH1,HIF-prolyl hydroxylase 1,HIFPH 1,HIFPH1,HPH 3,HPH-1,HPH-3,HPH3,Hypoxia inducible factor prolyl hydroxylase 1,Hypoxia-inducible factor prolyl hydroxylase 1,P4H1,PHD 1,PhD1,prolyl hydroxylase domain containing protein 1,Prolyl hydroxylase domain-containing protein 1

Background: The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene.

Poids moléculaire:

Observed_MW: 55kDa

Calculated_MW: 40kDa/43kDa

ID gène: 112398

UniProt: Q96KS0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cell RedoxHomeostasis