PCDHb5 anticorps (AA 278-307)

N° du produit ABIN657154

Cet anticorps Lapin Polyclonal détecte spécifiquement PCDHb5 dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour PCDHb5 anticorps (AA 278-307) (ABIN657154)

Antigène: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHb5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33054

Détail du produit anti-PCDHb5 anticorps

Épitope: AA 278-307

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PCDHB5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the Central region of human PCDHB5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur PCDHb5

Antigène: PCDHb5 (Protocadherin beta 5 (PCDHb5))

Autre désignation: PCDHB5

Sujet: This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

NCBI Accession: NP_056484

UniProt: Q9Y5E4