CAPN10 anticorps
Aperçu rapide pour CAPN10 anticorps (ABIN6572052)
Antigène
Voir toutes CAPN10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purification
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Immunogène
- Recombinant protein of human CAPN10
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Isotype
- IgG
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Indications d'application
- WB 1:1000 - 1:4000
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- CAPN10 (Calpain 10 (CAPN10))
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Autre désignation
- CAPN10
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Sujet
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Synonyms: Calcium activated neutral protease,Calcium activated neutral proteinase 10,Calcium-activated neutral proteinase 10,calpain like protease CAPN10,Calpain-10,Calpain10,CAN10,CANP 10,CANP10,CAPN 10,CAPN10,EC 3.4.22.,KIAA1845,NIDDM1
Background: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene.
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Poids moléculaire
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Observed_MW: 75kDa
Calculated_MW: 15kDa/29kDa/49kDa/57kDa/60kDa/74kDa
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ID gène
- 11132
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UniProt
- Q9HC96
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Pathways
- Positive Regulation of Peptide Hormone Secretion
Antigène
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