Nodal anticorps

N° du produit ABIN6572072

Cet anticorps Lapin Polyclonal détecte spécifiquement Nodal dans WB. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Nodal anticorps (ABIN6572072)

Antigène: Nodal (NODAL) (Nodal Homolog (NODAL))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nodal est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Nodal anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human NODAL

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Nodal

Antigène: Nodal (NODAL) (Nodal Homolog (NODAL))

Autre désignation: NODAL

Sujet:

Synonyms: HTX5,MGC138230,Nodal,Nodal Growth Differentiation Factor,nodal homolog (mouse),Nodal homolog,Nodal,Mouse,Homolog,NODAL

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.

Poids moléculaire:

Observed_MW: 44kDa

Calculated_MW: 39kDa

ID gène: 4838

UniProt: Q96S42

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance, Tube Formation, Positive Regulation of Endopeptidase Activity