MID1 anticorps (C-Term)
Aperçu rapide pour MID1 anticorps (C-Term) (ABIN657388)
Antigène
Voir toutes MID1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 575-603, C-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This MID1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human MID1.
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Isotype
- IgG
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Indications d'application
- WB: 1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- MID1 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
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Date de péremption
- 6 months
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- MID1 (Midline 1 (MID1))
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Autre désignation
- MID1
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Sujet
- The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Multiple different transcript variants are generated by alternate splicing, however, the full-length nature of some of the variants has not been determined.
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Poids moléculaire
- 75251
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ID gène
- 4281
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NCBI Accession
- NP_000372, NP_001092094, NP_001180206, NP_001180207, NP_001180208, NP_001180209, NP_001180210, NP_150632
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UniProt
- O15344
Antigène
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