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KIR2DS1 anticorps (AA 151-180)

KIR2DS1 Reactivité: Humain ELISA, WB Hôte: Lapin Polyclonal RB34046 unconjugated
N° du produit ABIN657823
  • Antigène Voir toutes KIR2DS1 Anticorps
    KIR2DS1 (Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1))
    Épitope
    • 6
    • 6
    • 6
    • 6
    • 5
    AA 151-180
    Reactivité
    Humain
    Hôte
    • 17
    Lapin
    Clonalité
    • 17
    Polyclonal
    Conjugué
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    Cet anticorp KIR2DS1 est non-conjugé
    Application
    ELISA, Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This KIR2DS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human KIR2DS1.
    Clone
    RB34046
    Isotype
    Ig Fraction
  • Indications d'application
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    KIR2DS1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Date de péremption
    6 months
  • Antigène
    KIR2DS1 (Killer Cell Immunoglobulin Like Receptor 2DS1 (KIR2DS1))
    Autre désignation
    KIR2DS1 (KIR2DS1 Produits)
    Synonymes
    anticorps CD158H, anticorps CD158a, anticorps p50.1, anticorps killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1, anticorps KIR2DS1
    Sujet
    Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
    Poids moléculaire
    33618
    ID gène
    3806
    NCBI Accession
    NP_055327
    UniProt
    Q14954
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