PNPLA6 anticorps (AA 1031-1080)
Aperçu rapide pour PNPLA6 anticorps (AA 1031-1080) (ABIN6579261)
Antigène
Voir toutes PNPLA6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1031-1080
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Fonction
- NTE Antibody
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Specificité
- NTE Polyclonal Antibody detects endogenous levels of NTE protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from the Internal region of human PNPLA6. AA range:1031-1080
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PNPLA6 (Patatin-Like phospholipase Domain Containing 6 (PNPLA6))
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Autre désignation
- PNPLA6
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Sujet
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Synonyms: PNPLA6, NTE, Neuropathy target esterase, Patatin-like phospholipase domain-containing protein 6
Background: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],
Gene Name: PNPLA6
Protein Name: Neuropathy target esterase
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Poids moléculaire
- 149 kDa
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ID gène
- 10908
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OMIM
- 603197
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UniProt
- Q8IY17
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Pathways
- Ribonucleoside Biosynthetic Process
Antigène
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