F11R anticorps (AA 191-240)

N° du produit ABIN6579557

Cet anticorps anti-F11R Polyclonal Lapin (ABIN6579557) détecte spécifiquement F11R dans WB, IHC, ELISA et IF. L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour F11R anticorps (AA 191-240) (ABIN6579557)

Antigène: F11R (F11 Receptor (F11R))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp F11R est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Détail du produit anti-F11R anticorps

Épitope: AA 191-240

Fonction: JAM-A Antibody

Specificité: JAM-A Polyclonal Antibody detects endogenous levels of JAM-A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human F11R. AA range:191-240

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur F11R

Antigène: F11R (F11 Receptor (F11R))

Autre désignation: F11R

Sujet:

Synonyms: F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321

Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008],

Gene Name: F11R

Protein Name: Junctional adhesion molecule A

Poids moléculaire: 32 kDa

ID gène: 50848

OMIM: 605721

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization