MACC1 anticorps (AA 411-460)

N° du produit ABIN6579596

L’anticorps anti-MACC1 Polyclonal Lapin est utilisé pour la détection de MACC1 dans des échantillons de Humain et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour MACC1 anticorps (AA 411-460) (ABIN6579596)

Antigène: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MACC1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MACC1 anticorps

Épitope: AA 411-460

Fonction: MACC1 Antibody

Specificité: MACC1 Polyclonal Antibody detects endogenous levels of MACC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human MACC1. AA range:411-460

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur MACC1

Antigène: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Autre désignation: MACC1

Sujet:

Synonyms: MACC1, Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5

Background: MACC1 is a key regulator of the hepatocyte growth factor (HGF, MIM 142409)-HGF receptor (HGFR, or MET, MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009],

Gene Name: MACC1

Protein Name: Metastasis-associated in colon cancer protein 1

Poids moléculaire: 96 kDa

ID gène: 346389

OMIM: 612646

UniProt: Q6ZN28