PAX5 anticorps (AA 171-220)
Aperçu rapide pour PAX5 anticorps (AA 171-220) (ABIN6579654)
Antigène
Voir toutes PAX5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 171-220
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Fonction
- Pax-5 Antibody
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Specificité
- Pax-5 Polyclonal Antibody detects endogenous levels of Pax-5 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from the Internal region of human PAX5. AA range:171-220
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- PAX5 (Paired Box 5 (PAX5))
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Autre désignation
- PAX5
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Sujet
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Synonyms: PAX5, Paired box protein Pax-5, B-cell-specific transcription factor, BSAP
Background: This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation.This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9,14)(p13,q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer
Gene Name: PAX5
Protein Name: Paired box protein Pax-5
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Poids moléculaire
- 42 kDa
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ID gène
- 5079
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OMIM
- 167414
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UniProt
- Q02548
Antigène
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