ZNF384 anticorps (AA 1-50)
Aperçu rapide pour ZNF384 anticorps (AA 1-50) (ABIN6579679)
Antigène
Voir toutes ZNF384 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-50
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Fonction
- ZNF384 Antibody
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Specificité
- ZNF384 Polyclonal Antibody detects endogenous levels of ZNF384 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized peptide derived from the N-terminal region of human ZNF384. AA range:1-50
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- ZNF384 (Zinc Finger Protein 384 (ZNF384))
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Autre désignation
- ZNF384
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Sujet
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Synonyms: ZNF384; CAGH1; CIZ; NMP4; TNRC1; Zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repeat-containing gene 1 protein
Background: zinc finger protein 384(ZNF384) Homo sapiens This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011],
Gene Name: ZNF384
Protein Name: Zinc finger protein 384
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Poids moléculaire
- 63 kDa
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ID gène
- 171017
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OMIM
- 609951
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UniProt
- Q8TF68
Antigène
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