HLA-DQ1/DQ2 anticorps (AA 131-180)

N° du produit ABIN6579687

L’anticorps anti-HLA-DQ1/DQ2 Polyclonal Lapin est utilisé pour la détection de HLA-DQ1/DQ2 dans des échantillons de Humain. Il a été validé pour ELISA, WB, IF et IHC.

Aperçu rapide pour HLA-DQ1/DQ2 anticorps (AA 131-180) (ABIN6579687)

Antigène: HLA-DQ1/DQ2 (MHC Class II HLA-DQ1/DQ2 (HLA-DQ1/DQ2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HLA-DQ1/DQ2 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Détail du produit anti-HLA-DQ1/DQ2 anticorps

Épitope: AA 131-180

Fonction: HLA-DQB1/2 Antibody

Specificité: HLA-DQB1/2 Polyclonal Antibody detects endogenous levels of HLA-DQB1/2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the Internal region of human HLA-DQB1/HLA-DQB2. AA range:131-180

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur HLA-DQ1/DQ2

Antigène: HLA-DQ1/DQ2 (MHC Class II HLA-DQ1/DQ2 (HLA-DQ1/DQ2))

Autre désignation: HLA-DQB1/2

Sujet:

Synonyms: HLA-DQB1, HLA-DQB, HLA class II histocompatibility antigen, DQ beta 1 chain, MHC class II antigen DQB1, HLA-DQB2, HLA-DXB, HLA class II histocompatibility antigen, DQ beta 2 chainHLA class II histocompatibility antigen, DX beta chain, MHC class II antigen DQB2

Background: major histocompatibility complex, class II, DQ beta 1(HLA-DQB1) Homo sapiens HLA-DQB1 belongs to the HLA class II beta chain paralogs. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains six exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marro

Gene Name: HLA-DQB1/HLA-DQB2

Protein Name: HLA class II histocompatibility antigen DQ beta 1 chain/HLA class II histocompatibility antigen DQ beta 2 chain

Poids moléculaire: 29 kDa

ID gène: 100507714

UniProt: P01920