OAS2 anticorps (AA 61-110)

N° du produit ABIN6579691

Cet anticorps anti-OAS2 Polyclonal Lapin (ABIN6579691) détecte spécifiquement OAS2 dans WB, ELISA, IHC et IF. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour OAS2 anticorps (AA 61-110) (ABIN6579691)

Antigène: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAS2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-OAS2 anticorps

Épitope: AA 61-110

Fonction: OAS2 Antibody

Specificité: OAS2 Polyclonal Antibody detects endogenous levels of OAS2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the N-terminal region of human OAS2. AA range:61-110

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur OAS2

Antigène: OAS2 (2'-5' Oligoadenylate Synthetase 2 (OAS2))

Autre désignation: OAS2

Sujet:

Synonyms: OAS2; 2'-5'-oligoadenylate synthase 2; (2-5')oligo(A) synthase 2; 2-5A synthase 2; p69 OAS / p71 OAS; p69OAS / p71OAS

Background: 2'-5'-oligoadenylate synthetase 2(OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],

Gene Name: OAS2

Protein Name: 2'-5'-oligoadenylate synthase 2

Poids moléculaire: '82 kDa

ID gène: 4939

OMIM: 603350

UniProt: P29728

Pathways: Hepatitis C