EIF5A anticorps (acLys47)
Aperçu rapide pour EIF5A anticorps (acLys47) (ABIN6579717)
Antigène
Voir toutes EIF5A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 11-60, acLys47
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Fonction
- Acetyl eIF5A/eIF5A2 (K47) Antibody
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Specificité
- Acetyl-eIF5A/eIF5A2 (K47) Polyclonal Antibody detects endogenous levels of eIF5A/eIF5A2 protein only when acetylated at K47.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogène
- The antiserum was produced against synthesized Acetyl-peptide derived from human eIF5A around the Acetylation site of Lys47. AA range:11-60
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Isotype
- IgG
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Indications d'application
- WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C/1 year
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Date de péremption
- 12 months
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- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
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Autre désignation
- eIF5A
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Sujet
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Synonyms: EIF5A2, Eukaryotic translation initiation factor 5A-2, eIF-5A-2, eIF-5A2, Eukaryotic initiation factor 5A isoform 2
Background: function:The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.,PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).,similarity:Belongs to the eIF-5A family.,tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.,
Gene Name: EIF5A2
Protein Name: Eukaryotic translation initiation factor 5A-2
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Poids moléculaire
- 16 kDa
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ID gène
- 56648, 56648
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OMIM
- 600187
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UniProt
- Q9GZV4
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Pathways
- Regulation of Muscle Cell Differentiation
Antigène
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