TUBA1A anticorps (acLys40)

N° du produit ABIN6579750

L’anticorps anti-TUBA1A Polyclonal Lapin est utilisé pour la détection de TUBA1A dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, IHC et IF.

Aperçu rapide pour TUBA1A anticorps (acLys40) (ABIN6579750)

Antigène: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBA1A est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TUBA1A anticorps

Épitope: AA 1-50, acLys40

Fonction: Tubulin α (Acetyl Lys40) Antibody

Specificité: Acetyl-Tubulin α (K40) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K40.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized Acetyl-peptide derived from human TUBA1A around the Acetylation site of Lys40. AA range:1-50

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur TUBA1A

Antigène: TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))

Autre désignation: TUBA1A

Sujet:

Synonyms: TUBA1A, TUBA3, Tubulin alpha-1A chain, Alpha-tubulin 3, Tubulin B-alpha-1, Tubulin alpha-3 chain, TUBA1B, Tubulin alpha-1B chain, Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-ubiquitous chain, TUBA1C, TUBA6, Tubulin alpha-6 chain, TUBA3C, TUBA2, TUBA3D, Tubulin alpha-3C/D chain, Alpha-tubulin 2, Alpha-tubulin 3C/D, Tubulin alpha-2 chain, TUBA4A, TUBA1, Tubulin alpha-4A chain, Alpha-tubulin 1, Testis-specific alpha-tubulin,

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species.This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.

Gene Name: TUBA1A/TUBA1B/TUBA1C/TUBA3C/TUBA4A

Protein Name: Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain/Tubulin alpha-3C/D chain/Tubulin alpha-4A chain

Poids moléculaire: 50 kDa

ID gène: 7846, 10376, 84790

OMIM: 602529

UniProt: Q71U36

Pathways: Dynamique des Microtubules, M Phase