EZH2 anticorps

N° du produit ABIN659002

Cet anticorps Souris Monoclonal détecte spécifiquement EZH2 dans WB, IF et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour EZH2 anticorps (ABIN659002)

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EZH2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 144CT2-1-1-5

Détail du produit anti-EZH2 anticorps

Homologie: Pr

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This EZH2 antibody is generated from mouse immunized with EZH2 recombinant protein.

Isotype: IgG1, Ig kappa

Information d'application

Indications d'application: IF: 1:10~50. IF: 1:25. WB: 1:2000. IHC-P: 1:10~50. IHC-P: 1:25. IHC-P: 1:25. IHC: 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-EZH2 (ABIN659002)

Zhang, Ji, Liu, Lei, Li, Ji, Yuan, Jiao: "Ezh2 regulates adult hippocampal neurogenesis and memory." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 15, pp. 5184-99, (2014) (PubMed).

Détails sur EZH2

Antigène: EZH2 (Enhancer of Zeste Homolog 2 (EZH2))

Autre désignation: EZH2

Sujet: This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Two transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 85363

ID gène: 2146

NCBI Accession: NP_001190176, NP_001190177, NP_001190178, NP_004447, NP_694543

UniProt: Q15910

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation