TGFB2 anticorps

N° du produit ABIN659106

Cet anticorps anti-TGFB2 est un anticorps Souris Monoclonal détectant TGFB2 dans WB, IHC (p) et IF. Adapté pour Humain.

Aperçu rapide pour TGFB2 anticorps (ABIN659106)

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFB2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 220ct16-4-3-1

Détail du produit anti-TGFB2 anticorps

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogène: This TGFB2 monoclonal antibody is generated from mouse immunized with TGFB2 recombinant protein.

Isotype: IgG1 kappa

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:100~1000. WB: 1:500-1:1000. IHC-P: 1:10~50. IHC-P: 1:10~50. IHC: 1:50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur TGFB2

Antigène: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Autre désignation: TGFB2

Sujet: This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1,7)(q41,p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 47748

ID gène: 7042

NCBI Accession: NP_001129071, NP_003229

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus