Thrombomodulin anticorps

N° du produit ABIN6653774

L’anticorps anti-Thrombomodulin Monoclonal Souris est utilisé pour la détection de Thrombomodulin dans des échantillons de Humain et Lapin. Il a été validé pour FACS, IHC (p) et IHC (fro).

Aperçu rapide pour Thrombomodulin anticorps (ABIN6653774)

Antigène: Thrombomodulin (THBD)

Reactivité: Humain, Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thrombomodulin est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: QBEND-40

Détail du produit anti-Thrombomodulin anticorps

Purification: Tissue Culture Supernatant containing 0.2M Tris/HCl pH7.4 and 5-10% foetal calf serum

Immunogène: Human Endothelium (Thrombomodulin).

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted at -20 °C.

Détails sur Thrombomodulin

Antigène: Thrombomodulin (THBD)

Autre désignation: CD141 / THBD

Sujet: CD141/Thrombomodulin is an exclusively endothelial cell surface glycoprotein that forms a 1:1 complex with thrombin. Binding of thrombin to this high-affinity receptor alters its specificity toward several substrates. The complex activates protein C approximately 1000 times faster than thrombin alone. Activated protein C degrades clotting factors V and VIII, thus, thrombomodulin converts thrombin into a physiologic anticoagulant. Thrombomodulin is also found in the circulatory and urinary systems, the physiologic significance of this is obscure.Synonyms: Fetomodulin, THRM, Thrombomodulin

ID gène: 9606

UniProt: P07204