CST3 anticorps (AA 31-146)

N° du produit ABIN6654028

L’anticorps Lapin Polyclonal anti-CST3 a été validé pour WB, ELISA et IHC (p). Il convient pour détecter CST3 dans des échantillons de Humain et Souris.

Aperçu rapide pour CST3 anticorps (AA 31-146) (ABIN6654028)

Antigène: CST3 (Cystatin C (CST3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CST3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CST3 anticorps

Épitope: AA 31-146

Purification: Antigen affinity purified

Immunogène: Human Cystatin C recombinant protein (amino acids K31-A146) was used as the immunogen for the Cystatin C antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Cystatin C antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant human protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Cystatin C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CST3

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: Cystatin C / Cystatin 3

Sujet: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.

UniProt: P01034