CST3 anticorps (AA 21-140)
Aperçu rapide pour CST3 anticorps (AA 21-140) (ABIN6654029)
Antigène
Voir toutes CST3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 21-140
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Purification
- Antigen affinity purified
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Immunogène
- Mouse Cystatin C recombinant protein (amino acids A21-A140) was used as the immunogen for the Cystatin C antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the Cystatin C antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ELISA (capture): 1-5 μg/mL (mouse recombinant protein)
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the Cystatin C antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CST3 (Cystatin C (CST3))
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Autre désignation
- Cystatin C / Cystatin 3
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Sujet
- Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. In humans, all cells with a nucleus (cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and body fluids. It is a potent inhibitor of lysosomal proteinases (enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases (it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Cystatin C belongs to the type 2 cystatin gene family.
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UniProt
- P21460
Antigène
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