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CD1b anticorps

Cet anticorps anti-CD1b est un anticorps Lapin Polyclonal détectant CD1b dans WB et IHC (p). Adapté pour Humain, Souris et Rat.
N° du produit ABIN6654113

Aperçu rapide pour CD1b anticorps (ABIN6654113)

Antigène

Voir toutes CD1b (CD1B) Anticorps
CD1b (CD1B)

Reactivité

  • 58
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Humain, Souris, Rat

Hôte

  • 30
  • 29
Lapin

Clonalité

  • 30
  • 29
Polyclonal

Conjugué

  • 31
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CD1b est non-conjugé

Application

  • 27
  • 21
  • 18
  • 14
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Purification

    Antigen affinity purified

    Immunogène

    Amino acids DKEVAELEEIFRVYIFGFAREVQDFAGDFQMKY were used as the immunogen for the CD1b antibody.

    Isotype

    IgG
  • Indications d'application

    Optimal dilution of the CD1b antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL

    Restrictions

    For Research Use only
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Stock

    -20 °C

    Stockage commentaire

    After reconstitution, the CD1b antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Antigène

    CD1b (CD1B)

    Autre désignation

    CD1b

    Sujet

    CD1b is a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens.

    UniProt

    P29016
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