P-Cadherin anticorps (AA 126-336)

N° du produit ABIN6654133

L’anticorps Lapin Polyclonal anti-P-Cadherin a été validé pour WB, ELISA et IHC (p). Il convient pour détecter P-Cadherin dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour P-Cadherin anticorps (AA 126-336) (ABIN6654133)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-P-Cadherin anticorps

Épitope: AA 126-336

Purification: Antigen affinity purified

Immunogène: Amino acids Q126-H336 from the human protein were used as the immunogen for the CDH3 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CDH3 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (recombinant human protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CDH3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: P-Cadherin / CDH3

Sujet: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

UniProt: P22223