CCL8 anticorps (AA 24-97)

N° du produit ABIN6654185

Cet anticorps anti-CCL8 est un anticorps Lapin Polyclonal détectant CCL8 dans IHC (p) et ELISA (Capture). Adapté pour Souris et Rat.

Aperçu rapide pour CCL8 anticorps (AA 24-97) (ABIN6654185)

Antigène: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL8 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Capture)

Détail du produit anti-CCL8 anticorps

Épitope: AA 24-97

Purification: Antigen affinity purified

Immunogène: Amino acids G24-P97 from the mouse protein were used as the immunogen for the Mcp2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Mcp2 antibody should be determined by the researcher.\. IHC (FFPE): 1-2 μg/mL,ELISA (Capture): 1-5 μg/mL (recombinant mouse protein)

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Mcp2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CCL8

Antigène: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Autre désignation: Mcp2 / Ccl8

Sujet: CCL8, also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. It is a small cytokine belonging to the CC chemokine family. The CCL8 protein is produced as a precursor containing 109 amino acids, which is cleaved to produce mature CCL8 containing 75 amino acids. The gene for CCL8 is encoded by 3 exons and is located within a large cluster of CC chemokines on chromosome 17q11.2 in humans. MCP-2 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, (that are implicated in allergic responses), and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors called chemokine receptors. These receptors include CCR1, CCR2B, CCR3 and CCR5.

UniProt: Q9Z121