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SPTA1 anticorps (AA 356-475)

SPTA1 Reactivité: Humain IHC (p) Hôte: Lapin Monoclonal SPTA1-2939R unconjugated
N° du produit ABIN6654212
  • Antigène Tous les produits SPTA1
    SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
    Épitope
    AA 356-475
    Reactivité
    Humain
    Hôte
    • 2
    • 1
    Lapin
    Clonalité
    • 3
    Monoclonal
    Conjugué
    • 3
    Cet anticorp SPTA1 est non-conjugé
    Application
    • 3
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    Purified
    Pureté
    Protein A affinity chromatography
    Immunogène
    A portion of amino acids 356-475 from the human protein was used as the immunogen for the recombinant Spectrin alpha 1 antibody.
    Clone
    SPTA1-2939R
    Isotype
    IgG kappa
  • Indications d'application
    Optimal dilution of the recombinant Spectrin alpha 1 antibody should be determined by the researcher.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)
    Restrictions
    For Research Use only
  • Buffer
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store the recombinant Spectrin alpha 1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • Antigène
    SPTA1 (Spectrin alpha Chain, Erythrocytic 1 (SPTA1))
    Autre désignation
    SPTA1 / Spectrin alpha 1 (SPTA1 Produits)
    Sujet
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous and chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin Ia and spectrin Ib are present in erythrocytes, whereas spectrin IIa (also designated fodrin alpha) and spectrin IIb (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
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