CD44v3 anticorps

N° du produit ABIN6654324

Cet anticorps Souris Monoclonal détecte spécifiquement dans IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour CD44v3 anticorps (ABIN6654324)

Antigène: CD44v3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3G5

Détail du produit

Purification: Purified

Pureté: Protein G affinity chromatography

Immunogène: An amino acid sequence from the variant 3 domain of CD44 was used as the immunogen for the CD44v3 antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Titering of the CD44v3 antibody may be required for optimal performance.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Restrictions: For Research Use only

Stockage

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the CD44v3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détail du antigène

Antigène: CD44v3

Sujet: This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 Molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. It is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.